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Background
of Spirulina:

Spirulina
is the blue-green multi-cell algae, which cannot be
seen by naked eyes. Spirulina is a spiral stem generally
found in fresh water, brine and brackish water, consisting
of 60-70 % protein in dry weight. The protein elements
consist of 18 types of amino acids, several vitamins,
such as vitamin A, B, E, H and minerals, fatty acids
necessary to the body.
Spirulina has been studied under various the scientific researches
for more than 20 years and consumed in more than 70 countries worldwide.
Presently, it is very useful nutritious food for preventive and
symptomatic treatment, such as antiviral activity, blood nourishment,
enhancing immunity against bacteria or foreign substances for body
and recovery during convalescent period.
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| Spirulina,
the worldwide ideal algae:
Several
living beings are depending on each other for their
survival. Likewise, human being also need plants
and animals as their food. These natural foods
are important for the survival of human beings
because all these food play major role for human
body and soul. Thus, it is necessary for us to
select the best one (food) for our healthy body
and cheerful mind, which is the most important
thing for all human being. Now that the best natural
food has been discovered, that is a “Spirulina” algae.
Spirulina may not be the acquainted name to most people, but
it is one kind of algae found among the ancient age. Thousand
years ago, the Mexican and African used spirulina as daily
food. Even though spirulina were consumed for long time, it
has just been widely known in modern industry for only 30 years.
Spirulina,
the ideal food will result in better health and
enhance immunity for the millions of people in
several countries. In addition to being an excellent
food supplement, spirulina also conveys nutrients,
minerals and vitamins to human body system more
efficiently than other nutritious food.
Spirulina is not a medicine
but being perfect and excellent nutrient consisting of 25 types of natural minerals
and vitamins, which are sufficient for healthy and long life, homeostasis, reducing
exhaustion and strengthening the body.
From the pharmacological
researches about safety of spirulina, the project conducted by Prof. Kenichi
Akatzuka, M.Sc., Ph.D., Faculty of Pharmaceutics, Meiji University of Japan (Information
from translation book Vol. 105, Office of the National Research Commission) revealed
that the safety of spirulina are as follows;
1. Being the product with high purity
2. No side effects even after continuous consumption
3. No toxicity or side effects in case of overdose
4. Improve health and increase immunity with daily consumption
of spirulina.
Spirulina is, therefore, considered as a part of health improvement
for all consumers who need the perfection from nutrients in
spirulina.
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1. What is spirulina?
Spirulina is the micro-algae that cannot be seen by
naked eyes, being multi-cell blue green algae,
grown in warm
and brackish water, with the properties as alkaline.
The strain, researched by more than 30 countries
worldwide, is Platensis. The root of “spirulina” comes
from Latin as helix or spiral that means the spiral
shape like a whorl as Deurben; the German scientist
had named
it as spirulina in 1927.
2. Why is spirulina called an ideal food of mankind?
Spirulina consists of more concentrated nutrients than
any other food, vegetables, seeds or plants, respectively.
More than 60 % protein, of which all are easy
to digest, having beta-carotene, vitamin B12, folic acid, minerals
and essential fatty acids. These elements turn out
spirulina
to be distinctively different
from other food.
3. Are there any researches related to spirulina?
Spirulina has been researched by more than 4,000 scientists
worldwide in the past 40 years.
4. Is spirulina safe for consumption?
Spirulina is the bluish green algae with its long history
about safety for consumption as the Mexican has consumed
spirulina for long time. Recently,
spirulina is adapted as food products in more than 70 countries worldwide.
Furthermore, UN has suggested it (spirulina) as the ideal food for mankind,
and WHO has also intimated spirulina as the safe food with excellent nutrition
especially for children.
5. Is there any toxic remained in spirulina?
Spirulina is absolutely free from toxic without any
remains of residue. It is consumed for health improvement.
6. How spirulina is different from other natural nutritious
food?
Other natural nutritious food possesses different properties
for nourishment, whereby some of them must be consumed
under the supervision of the physician
or in limited quantity to prevent some side effects, which may occur. Undoubtedly,
spirulina is the natural food and consumable at any time without any side
effect.
7. What is the usefulness of spirulina to body?
The scientists all around the world have studied for
more than 40 years and concluded that spirulina has
more health benefits to body in the following
ways;
1. Enhance immunity or immune response
2. Support heart and reduce cholesterol
3. Help to improve the digestive system
4. Naturally help the detoxification process
5. Reduce the risk of cancer and increase the antioxidant capacity
8. What are the nutritious elements of spirulina?
Spirulina consists of several nutritious elements,
which are important for health improvement. These
elements are proteins, essential amino acids, non-essential
amino acids, minerals, vitamins, fat, sugar, mineral salts and calories.
9. What is the suitability of spirulina?
Spirulina is suitable to use as nutritious food not
only for healthy, unhealthy person but also for those
who have the following symptoms; easily tired,
easy to catch cold, insufficient consumption of green or yellow vegetables,
dizziness, lack of some nutrients, skipping of meals like breakfast or
person under diet.
10. After being consumed, which factors induce body
response against spirulina?
Spirulina uptake is able to cause immediate or slow
result of body response, depending on several factors
including age, stress, eating habits, chemical
residues in body and severity of diseases. Spirulina should be consumed continuously
and sufficiently a long with proper exercise and adequate rest.
11. What is the appropriate quantity for consuming spirulina?
The appropriate quantity is based on the suggested
quantity, such as the healthy person should take
6 capsules a day, 2 capsules each meal.
Person on diet should take 6 capsules each meal, 3 meals a day before food,
etc. However, spirulina can be consumed unlimitedly without any side effects
due to its toxic free or any remaining substance.
12. Will the nutritious value be decreased if spirulina
powder is removed from capsule?
Removal of spirulina powder from capsule will not decrease
the nutritious value. The other way to uptake spirulina
is to mix spirulina with milk or juices,
etc.
13. Why do some interactions occur after spirulina being
consumed?
The body interaction against spirulina, such as skin
allergy, mild fever, is only temporary incident,
which shall be automatically recovered within 2-3
days. This interaction can be caused by unhealthy and/or insufficient consuming
of spirulina. In contrast, there are no side effects on a healthy person.
Consumption
of spirulina would nourish and balance your health (as seen on page 19).
14. Is it possible to consume spirulina with medicine?
Spirulina is not a medicine, yet it is the natural
food containing with 5 groups of essential nutrients.
It is, therefore, consumable with other medicines
and also helps body absorbing full benefits from medicine.
15. Can the patient at the recovery stage take spirulina?
A patient at the recovery stage needs nutrients in
order to comeback at normal stage since spirulina
has plenty of several nutrients, which is suitable
as food supplement for all patients.
16. How does spirulina benefit to one who insufficiently
takes green or yellow vegetables?
Person who does not consumes green or yellow vegetables
can take spirulina as food supplement because it
consists of vitamins, mineral salts and other
pigments, such as chlorophyll, vitamin A, beta-carotene, etc. to substitute
the natural compositions from vegetables.
17. Should children take spirulina?
Protein in spirulina will develop and enhance the growth
of children. They can consume spirulina by mixing
with milk if they cannot directly take the
capsule.
18. Can spirulina reduce stress?
Person under stress or mental problems may be influenced
by diseases, such as peptic ulcer or hypertension.
Those who suffered from such disease should
take some sources of food containing large quantity of vitamin B complex,
essential amino acids, essential fatty acids, which are mostly found in
spirulina. It is, therefore, considered as a good
source of food supplement for reducing
serious illness and strengthening health of all patients.
19. How does spirulina suit for the patient
suffering from pepticulcer?
Either the medicine for peptic ulcer treatment consists
of chlorophyll, or does spirulina. Due to the property
of chlorophyll-contained in spirulina,
it can reduce the inflammation of stomach. So, it is believed that spirulina
might help treating peptic ulcer.
20. Spirulina and elderly patient
Older person usually has some chronic diseases, such
as hypertension, cardiopathy, and some types of cancer,
diabetes, gout, cataract, liver disease or renal
disease. Spirulina will improve health of the elderly person. Some researches
in Japan has found out that more than 70 % of people taking spirulina were
over 50 years old, whereby 57 % were female. They mentioned that the purpose
of taking spirulina was for treating some diseases, health improvement
and food supplement, respectively.
This can be concluded that spirulina is considered as the life-extending
medicine for old age, because it can well protect some elderly diseases.
21. Spirulina and youngster
Arginine is an essential amino acid containing in semen
for approximately 80 %. Lacking of arginine may cause
sexual disability or sterility. Tryptophan
is also an amino acid affecting to the confidence of male sexual power.
In addition, zinc is a mineral useful for treating
abnormal sexual function.
As spirulina consists of amino acids, calcium and zinc that resulted to
sexual potency. So, spirulina is suitable for both
young female and male.
22. Does spirulina help reduce cholesterol?
Recently, it is widely recognized that cholesterol
increases the risk of heart attack, which is the
most serious problem of public health. Reduction
of
cholesterol is another way to decrease risk of cardiopathy. Consequently,
spirulina is the natural food that helps in reducing cholesterol.
Some researches mentioned that taking spirulina could reduce cholesterol.
This may be because body had received GLA (Gamma-linolenic acid), which
is mostly
found from spirulina.
23. How does spirulina help sportsman?
Sportsman needs more and extra nutrients from any source.
According to the composition spirulina, is composed
of special concentrated nutrients that
are suitable for exercise and hard training. Taking spirulina before training
and competition would help energize and strengthen muscle. Because spirulina
comprises of more than 60 % of proteins and amino acids, so it helps in
reducing calories, which is the important factor
for weight control in sports events
and competition.
24. What is the usefulness of beta-carotene in spirulina?
Beta-carotene is an anti-cancer substance. Several
researches revealed that taking beta-carotene is
related to cancer prevention. Beta-carotene is a
source of vitamin A, which is mostly found in spirulina 20-25 times more
than in carrot. In addition, beta-carotene can help protect chemical substances
causing malignant tumor, defending chromosomal changes causing cancer and
enhancing immune system. Since beta-carotene exhibits high anti-cancer
property, spirulina can be replaced for vegetables
or fruits.
25. How does spirulina help digestion and absorption
system in the body?
There is one microorganism
in human intestine called lactobacillus, which helps
in digestion and absorption
of food, prevent infection and activate the immunity.
With its enormous benefits, spirulina has become a great hit to take
lactobacillus as a food supplement. Spirulina can activate
lactobacillus in intestine and
help improve absorption of vitamin B2. Taking spirulina is useful to
increase lactobacillus in intestine and absorption
of vitamin B1 and other vitamin.
26. Hepatitis and spirulina
Hepatitis is caused by several factors, such
as virus infection, non-hygienic food or allergic
side effects from medicine. Currently, the
way
to treat
it is to take sufficient rest and also eat more nutrients and proteins.
Spirulina can help to abate chronic and serious
hepatitis because it is composed of
vitamin B12 and 60-70 % protein; protein is the important factor
for hepatitis treatment. Several researches
by Japanese
physicians found that spirulina
can help to abate hepatitis.
27. Spirulina and patient with pancreatitis
Inflamed pancreas is caused by self-digestion of liver,
drinking too much liquor, gallstone or eating highly
fatty food. The treatment is to solve it at its
origin; for instance, if the disease is caused from drinking too much alcohol,
stop drinking can prevent it. The other treatment may be carried out by
eating food with high nutrients. As spirulina is
rich in protein, high digestion
rate, low fat, high vitamins and mineral salts. Spirulina shall not cause
any problem to digestion in the patients suffering from liver disease (pancreatitis).
28. Spirulina and hair loss
Spirulina is able to reduce rate of hair loss, activate
hair growth, as spirulina consists of necessary fatty
acids (sometimes called vitamin F), including
linoleic acid and arachidonic acid which are the important fatty acids
for nourishing hair, skin and nail. Meanwhile, they
are useful to hair root,
leading to the beauty of hair.
29. How does spirulina help to treat anemia?
Spirulina consists of high protein, chlorophyll, vitamin
B12 and folic acid; therefore, it is able to increase
the quantity and efficiency of red blood
cells, which will result in more exchange of oxygen for better circulation
within 30 days. Spirulina also gives excellent nutritive values to the
patients who long time- lack nutrients and improves
health by providing sufficient
vitamin E, B12 and folic acid.
30. Optic problem and spirulina
At present, more old age people suffer from ophthalmic
problems, such as cataract, abnormal retina and the
symptom of other diseases, such as diabetes and anemia.
Several tests from Japanese physicians were found that spirulina could
help
treat cataract and stop the development of the disease that affects vision.
In the hypertensive patient or clogged blood vessels in retina, spirulina
can be taken with medicine for better results.
31. Is spirulina easily digested in human body?
95 % of spirulina can be easily digested in human
body as spirulina has thin cell membrane and
consists of proteins, polysaccharides, and enzymes
that can
be quickly dissolved into body. It is, therefore, considered as
easily digestive food. Spirulina is suited to those
who
have problems about digestion or esophageal
including also those old age people.
32. Can we eat only spirulina as food?
Spirulina is rich and full of nutritious values yet
human body should consume different kinds of food
and should not consume only one type of food to prevent
any lack of nutrient. Spirulina should be consumed together with food or
as food supplement to enhance body health.
33. Is it true that spirulina is useful for all age?
Spirulina is useful for people of all age; for instance,
spirulina is easily digested in the old age person,
whereas the sportsman shall receive great energy
from spirulina. Children would receive nutritive
values
for their growth, or the pregnant women will get
folic acid and protein from spirulina, etc.
34. Is spirulina internationally accepted?
Spirulina has been accredited and certified by the
leading institutes of the world, such as;
1967: “The International Conference on Applied Microbiology” has
announced that “Spirulina must be considered as an important future food
source”.
1974: UN has announced in the World Food Conference that spirulina
was “The
most ideal food for mankind”.
1974: FAO (Food and Agriculture Organization) has introduced that spirulina
was “The best food for tomorrow”.
1981: FDA (Food and Drug Administration) of USA has certified that spirulina
is “The healthy and safety product free from side effects”.
1983: IFE (International Food Exposition) held in East German has awarded
the prize “The best natural food” to spirulina.
1992: WHO (World Health Organization) has introduced that spirulina
was “The
healthy product in 21st decade”.
35. Does the manufacturer of spirulina achieve the standard?
The manufacturing unit of spirulina is Advanced Spirulina
Biotechnology Co., Ltd, located at 351, Moo 1, Tambon
Sala, Amphur Koh Kha, Lampang, 52130.
The head office is at 444, Olympia Thai Tower, 10th Floor, Ratchadapisek
Road, Samsennok, Huaykwang, Bangkok, 10320. It is the international standard
company duly established on 1 April 1999 with the initial registered capital
1,000,000 Bahts. Recently, its registered capital has increased to 25,000,000
Bahts, which has led the company to fluently operate its business and been
recently supported and also promoted by the Board of Investment. All products
under the name of Advanced Spirulina Biotechnology (ASB) has been strictly
examined through laboratory tests, which are more than 20 steps under the
high experienced QC control team works throughout the manufacturing processes
to ensure that the consumer will be served with high nutritive value products
according to the international standard in every respect.
36. Is there any organization to certify the correctness?
Spirulina from Advanced Spirulina Biotechnology Co.,
Ltd. is served with high quality and standard, and
has been certified by FDA No. 52-1-02643-1-0002
to certify the safety for consumption and by the Islamic Institute according
to the Halal certificate No. 471(8)/2543 from the ICOT.
37. How about the service system within the organization?
There are several types of activities within the organization,
such as 5C activities, GMP, HACCP and ISO 9001: 2000
standards.
38. Which organization has been supported the company?
Advanced Spirulina Biotechnology Co., Ltd. has been
promoted from BOI and Small Industrial Finance Corporation,
and is also the member of Traditional Medicine
Manufacturer and Seller Association (Thailand).
39. How the consumers can rely on the products?
The consumer can rely on the products, which have been
passed through the modern manufacturing process with
automatic and semi-automatic machines of ultramodern
technology. The company can certify that the products has achieved the
standard,
safety and high quality as guaranteed by the reward of the best factory
for food and beverage industry in 2000 and 2002 from
the factory contest office
duly consisted with the representative from 5 ministries to ensure the
manufacturing quality of the company.
40. The policy of the company
The goal of Advanced Spirulina
Biotechnology Co., Ltd. is to manufacture and distribute
food supplement
products extracted from spirulina algae by emphasizing
the efficiency and improvement of the product, proposing new products
to correspond with the demand of dynamic market, being
the leader in both
domestic
and international spirulina market and the leader in development, breeding
and technology from new innovation.
Spirulina should be taken as food to supplement the
insufficient nutrients daily and able to take with
medicine or other
food supplements.
41. Can children and pregnant woman women take spirulina
capsules?
Children should take at least 2 capsules a day by taking
with milk in the morning and evening. Pregnant women
should be advised by physicians before taking spirulina
capsules.
42. Should we take spirulina capsules before or after
meals?
Spirulina capsules are nutritional supplements, which
can be taken before or after meals. However, they
should be taken 30 minutes before meals to get the
best absorption.
43. Can patients with heart disease, impaired kidney
function, cancer or AIDS undergoing conventional therapy
take spirulina capsules?
Patients should take medicine as prescribed by physicians
and take spirulina capsules as nutritional supplements
for health improvement and renew body cells.
The spirulina capsules may be taken alternately with conventional medicines.
For example, if the patients take the medicines after meals, they may take
the spirulina capsules before meals. If they take the medicines both before
and after meals, they may take the spirulina capsules at bedtime.
44. How to take spirulina capsules to lose weight or
firm body?
During the first week, take 3 spirulina capsules 30
minutes before meals, then increase the amount by
taking 5-6 capsules in the second week, and maintain
the amount of 6 capsules before each meal, three meals a day for 6 months.
Within the first month, limit the amount of diet, for example, after taking
5 capsules with 2 glasses of water, you will feel full and then you may skip
the meal while receiving plenty of nutrients from spirulina. However, you
should
eat at least one meal a day. If you feel hungry between meals, you should
take some fruits, such as guava to limit the intake
calories. This will help you
gradually losing weight at least 4-6 kg within 3 months.
45. The label on the bottle said “contained 100%
spirulina” What does it mean?
Each capsule contain 100% spirulina powder. This means
that spirulina powder is 500 mg, and capsule shell
is about 100 mg approximately. The content in
the capsule is 100% spirulina. Other types of products, excluding our spirulina
capsule, may contain starch as filler, therefore; consumers would inevitably
receive starch and may risk to molds or fungi growing with the moisture in
the starch. Some tablets are protected from mold by waxing.
46. A different between drug and dietary supplement
The term “drug” means articles using
for diagnosis, treatment or prevention of disease in
human being or other animals; and pharmaceuticals
or partially processed pharmaceuticals that intended to affect the structures
or functions of human body or other animals.
Drug is known as one of the four essentials of life. Although the use of
drug is generally beneficial, it can have some severe side effects or adverted
effects
to some extents. It is important to take with caution and consult to physicians
or pharmacists before taking any drug.
“Dietary supplement” is not a “drug”. It generally contains
an optimal combination of nutrients from natural sources. It is good source
for correcting nutritional deficiency as well as promoting health. Minor side
effects
from using dietary supplement may happen, especially when compared to drug.
Allergic reaction to dietary supplement may sometimes be rare and mild.
To get the most benefit from taking dietary supplement, it is advised to consult
experts or search for more information.
There are examples of dietary supplement from natural sources including spirulina,
wheat germs and cereals, which are good sources of plant proteins, vitamins
and minerals. However, to achieve optimal health, it is recommended to have
a balanced diet, doing regular exercises, avoid stress and take some good
rests.
47. What are the company policies related to quality
control and how can the company control the quality of
the products?
The company’s vision is to be the best healthcare
product provider for Thai people. The company recognizes
the importance of setting up the quality
assurance system in order to win the confidence and build trust of customers
in health food products manufactured by the company. This can be achieved
by operating and applying various stages of quality
control including GMP, HACCP
and ISO 9001.
Notes: -
- GMP (Good Manufacturing Practice) establishes the criteria of guidelines
essential for manufacturing and quality control in order to be complied by
manufacturers ensuring safe manufacturing practice of food.
- HACCP (Hazard Analysis and Critical Control Point) is the system for hazard
analysis and control of critical points in order to protect the consumers
from any harmfulness. This may be termed as CCP in abbreviation. It refers
to strict
monitoring of every critical point ascertaining that the food is safe for
consumers according to the international standards for quality assurance
in manufacturing
and service industries.
- CODEX, in food manufacturing, there are several steps in manufacturing
and quality control in order to produce food safely and can be trusted by
the customers
according to the International Food Guidelines or CODEX. The company follows
Good Manufacturing Practice (GMP) of food, therefore; it can be reassured
that the company can produce high quality food without any contamination,
which
may be harmful to the consumers. CODEX is the abbreviation of FAO/WHO commission
known as Codex Alimentarius Commission (CAC). Codex Alimentarius comes from
Latin words meaning food code. Thus, in general sense, Codex Alimentarius
means international guidelines and regulations related to food.
48. Which organization supports the company?
The manufacturer of spirulina was set up by standard
procedures and was supported by Board of Investment
(BOI) and Financial Institute for Small to Medium
Enterprises.
The spirulina was manufactured under high standards and received the Award
for Distinction in Food and Drink Industry of the year 2000 and 2002 from
Ministry of Industry. Thus, the consumers can trust our products undergoing
modern manufacturing
technology.
49. How does the company improve its organizing management?
In the present world, things change quickly resulting
in “endless demand
for satisfaction of the customers”. The company has developed
its organizing management and administration by having consulting services
for customers and
personal training in the most efficient manner. The company acquires
a team of professional consultants with high levels of intellectual
power
and expertise
in order to respond to the demand and customer satisfaction.
50. What are the future plans of the company?
The company is improving its potency in all aspects
in order to be the leader in manufacturing
spirulina in a complete cycle. In addition, our company
has the standard algae culturing ponds with the Award of Distinction
in
the year 2000 and 2002 for raising enough quantity
of raw materials for producing
health food. The company is now in the stage of initiating the SPA
HEALTH & BEAUTY
RESORT. The company also produces 15 natural beauty products, such
as spirulina shampoo and hair conditioners, spirulina
facial and body scrub, spirulina
whitening mask and spirulina nourishing mask. Besides, the company
has developed the additional 16 health and beauty
products containing mixture of spirulina
and various herbs for export. The company has the confidence to provide
complete service to customers since we are ready
to be the leader in the spirulina
business.
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Type of disease
|
Recommended quantity per day
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Duration
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| 1. Diabetes |
3 times @ 5 capsules |
The sugar level shall be reduced to almost normal
within 2 months. |
| 2. Anemia |
3 times @ 5 capsules |
Recovered within 15-30 days |
3. Chronic hepatitis
Acute pancreatitis
Viral hepatitis
|
3 times @ 5 capsules |
Recovered within 1-3 months |
| 4. Peptic ulcer |
3 times @ 5 capsules |
Better symptom within 1-3 months |
| 5. Cirrhosis of liver |
10 capsules before drinking alcohol |
Help to prevent the Cirrhosis and drunk |
| 6. Cataract |
2-3 times @ 6 capsules |
Can be continuously used |
| 7. Hair loss |
2 times @ 4 capsules |
30-90 days |
| 8. Health improvement |
2 times @ 2-3 capsules |
an be continuously used |
| 9. Sportsman |
2 times @ 3 capsules |
Can be continuously used |
| 10. Old age disease |
3 times @ 6 capsules |
Can be continuously used |
| 11. Exhaustion, dizzy |
3 times @ 5 capsules |
Recovered within 15-30 days |
| 12. Pollution from heavy metals |
3 times @ 6 capsules |
Can be continuously used |
| 13. Fatty disease |
3 times @ 6 capsules |
Can be continuously used (before meal 15-30 minutes) |
| 14. Pimple, blemish |
3 times @ 5 capsules |
30-60 days |
| 15. Allergy |
3 times @ 6 capsules |
Can be continuously used |
| 16. Loss of white blood cell |
3 times @ 6 capsules |
Can be continuously used |
| 17. Toxic from radiation |
3 times @ 6 capsules |
More than 45 days |
| 18. Stress |
3 times @ 5 capsules |
Can be continuously used |
| 19. High cholesterol |
2 times @ 5 capsules |
30-60 days |
| 20. Diarrhea, vomiting |
3 times @ 5 capsules |
15-30 days |
| 21. Cancer |
3 times @ 5 capsules |
Can be continuously used |
| 22. Renal disease |
2 times @ 2 capsules |
Can be continuously used |
The consumers of spirulina can be classified into 3
groups
Suggestive quantity of taking spirulina is shown on
above, which is the quantity for treatment of the patient
with alternative medicine. This information is complied
from partial information from translation paper of National
Research Commission Office Volume No. 105. If you are
currently treated by modern medicine, it is suggested
to take modern medicine according to the suggestion of
the physicians and can safety take spirulina as food
supplement for health improvement.
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| Interaction |
Possible cause |
|
Fever or mild fever
|
Protein
in spirulina and other nutrient would activate
body to emit heat, which increase body temperature
to build up new cells
|
|
Fever,alert and sleepless
|
Caused
by the biotransformation of excess fat of body
to heat
|
|
Black
or green feces
|
The green color is caused by green pigment in spirulina.
|
|
Stomachache
|
Abnormal
digestive system, wound in the bladder
|
|
Difficult
breathing
|
Gout, uric acid, asthma, allergic
|
|
Drowsy,
exhaustive hands and legs
|
Urine
is in alkaline condition, liver failure, gout
|
|
Nausea,
diarrhea, constipation, hiccup
|
Found
in nutrient-lacking person, take too much dietary
medicine
|
|
Small
pimple, rash on skin, drowsy
|
Resulted
from detoxification process, allergic or abnormal
function of liver
|
|
Cold,
flu, sore throat
|
Resulted
from dispersion of virus and bacteria through body
|
|
Irregular
menstruation
|
Occurred
while body is under hormone-balancing process and
repairing new cells
|
|
Catarrh,
asthma, productive cough
|
Malfunction
of respiration system, increase immunity and get
rid off virus
|
|
Bloating
from too much gas
|
Malfunction
of renal, peptic ulcer, abnormal digestive system
|
|
Nosebleed
|
Anemia,
sinus, weak and small blood vessel
|
|
Rectum
pain or irritated, bleeding through rectum
|
Hemorrhoids,
detoxification, accumulation of virus and bacteria
|
| No
reaction
|
Body
is almost healthy in case of continuous eating
spirulina or otherwise less eating spirulina
|
Remark: These interactions are normally shown for 2-3
days or longer depending on individual’s health.
The interaction showed in this page is derived from scientific
researches, which can be indicated as follows: -
As the human body receives several nutrients from spirulina,
it helps generate and repair cells including red
and white blood cells. The elements in the blood
cells can replenish body to efficiently resist against diseases and dispose
the strange substances and toxic. This will improve
body’s immune system. The
duration of these interactions is based on each individual’s health
and will be automatically recovered within 1-2 weeks. While undergoing
these interactions,
one should continuously have spirulina for health improvement and detoxification
of toxic substances in the body.
|
|
 |
|
| Nutrients of spirulina |
| Protein |
71.1
%
|
| Essential
amino acids |
| Isoleucine |
4.13%
|
| Leucine |
5.50%
|
| Lysine |
4.0 %
|
| Methionine |
2.17%
|
| Phenylalanine |
3.95%
|
| Threonine |
4.17%
|
| Tryptophan |
1.13%
|
| Valine |
6.0 %
|
| |
| Non-essential
amino acids |
| Alanine |
5.82%
|
| Arginine |
5.98%
|
| Aspartic acid |
6.32%
|
| Cystine |
0.67%
|
| Glutamic acid |
8.94%
|
| Glycine |
3.46%
|
| Histidine |
1.08%
|
| Proline |
2.97%
|
| Tyrosine |
4.60%
|
| Serine |
4.0 %
|
| RNA |
3.5 %
|
| DNA |
1.0 %
|
| |
| Essential
fatty acids |
mg./kg.
|
| Palmitic acid |
21,141
|
| Gamma-linolenic acid |
11,970
|
| Linoleic acid |
13,785
|
| Palmitoleic acid |
2,035
|
| Oleic acid |
3,009
|
| Stearic acid |
353
|
|
| Vitamins |
mg./kg |
| Thiamine B1 |
55.0
|
| Riboflavin B2 |
40.0
|
| Niacin B3 |
140
|
| Pyridoxine B6 |
3.0
|
| Cyanocobalamin B12 |
2.0
|
| Tocopherol E |
190.0
|
| Vitamin K-1 |
22
|
| Inositol |
350
|
| Folic acid |
0.5
|
| Pantothenic acid |
11.0
|
| Biotin (H) |
0.4
|
| |
|
| Pigments |
mg./kg. |
| Beta-carotene |
1,700
|
| Carotenoids |
4,000
|
| Phycocyanins |
140.0
|
| Chlorophyll |
7,600
|
| |
|
| Minerals |
mg./kg. |
| Calcium |
1,315
|
| Magnesium |
1,915
|
| Potassium |
15,400
|
| Phosphorus |
8,000
|
| Sodium |
412
|
| Manganese |
25
|
| Zinc |
39
|
| Copper |
12
|
| Chromium |
2.8
|
| Iron |
580
|
|
These nutrients are pure natural substances unlikely to
the vitamin substance and/or mineral that are synthesized
from chemicals. It is, therefore, not accumulated in body
due to long time-consumption
|
|
 |
|
Important nutrients found in
spirulina for contributing the prevention, treatment, and
inhibition of the organs of body according to the nutrition
principles
• Activating the function of brain
- Niacin, Valine, Isoleucine, Leucine, Zinc, Vitamin B1, Vitamin B3
• Emotion controlling
- Inositol, Phenylalnine, Vitamin B1, Vitamin B3
• Protecting brain fiber
- Serine, Phenylalanine, Vitamin B6
• Preventing hair loss
- Linoleic acid, Gamma-linolenic acid, Zinc, Arachidonic acid, Inositol, Biotin
• Optical problem
- Beta-carotene (Vitamin A), Riboflavin
• Listening
- Histidine
• Reducing stress
- Methionine, Pantothenic acid, Tryptophan, Phenylalanine, Inositol
• Oxygen generating
- Glutamic acid, Tocopherol
• Increasing the capacity of red blood cells
- Chlorophyll, Vitamin B12, Folic acid, Alanine, Iron
• Cardiopathy
- Gamma-linolenic acid, Lactic acid, Celenium, Vitamin E, Vitamin B6
• Hypochromasia
- Iron, Vitamin B12, Magnesium, Vitamin B6, Chlorophyll, Folic acid
• Reducing cholesterol
- Gamma-linolenic acid, Inositol, Niacin
• Reducing inflamed pancreas
- Cysteine
• Gastropathy
- Chlorophyll
• Skin nourishment
- Chlorophyll, Tyrosine, Vitamin E, Phycocyanin
• Cancer
- Beta-carotene, Vitamin E, Phycocyanin
• Hepatitis
- Protein, Inositol, Methionine, Leucine, Isoleucine
• Improving sexual capacity
- Tryptophan, Arginine, Zinc, Vitamin E, Vitamin F
• Supplementing digestion and absorption
- Iodine
• Weight control
- Phenylalanine, Tyrosine, Chromium
• Diabetes
- Magnesium, Chromium, Vitamin B1, Vitamin B2, Vitamin B3
• Blood breaching
- Arginine
• Maintaining sugar level in blood
- Potassium, Chromium
• Gout, Rheumatism
- Serine, Pantothenic acid
• Enhancing immunity
- Alanine, Beta-carotene, Vitamin E, Pantothenic acid
• Increasing renal function
- Phosphorus
• Improving energy synthesis
- Aspartic acid, Glycine, Vitamin B complex
• Osteoporosis (Bone problem)
- Calcium, Zinc, Phosphorus, Magnesium, Potassium
|
|
 |
|
How spirulina improve our health
and prevent diseases?
At present,
the environment is contaminated with toxic substances,
including pollution of air, food, water and
stress, which are major cause of health related
problems
and especially to our beloved people.
Spirulina algae
Spirulina is the ideal food supplement. The scientists discovered it since
the ancient age as the miracle plant originated for more than 3,500 million
years. Recently, more than 4,000 scientists in more than 20 countries had
studied, researched and found that spirulina is an excellent food supplement
and could safely help in abating several serious diseases and enhance immunity
at all ages.
Help to control overweight problems
The proper and better way of dieting should not cause deterioration, exhaustion
and emotional change. This condition can be substituted by spirulina, which
is the perfect food supplement with low fat and calories resulting in the
healthy weight lost. Phenylalanine would activate the metabolism of our body,
while tyrosine helps controlling eating habit.
Control diabetes and sugar
Too much sugar level in the body causes diabetes, which is difficult to treat
but controllable. The nutrients that are specially provided for diabetic
patients are beta-carotene, vitamin A, B1, B2, B5, B6, B12 and C, Manganese,
Magnesium, Potassium and Zinc, as those are necessary for balancing the body
condition.
Abate hair loss
Spirulina consisted of high protein, vitamin and chlorophyll, it is able to
stop hair loss and activate hair to be blackening. Vitamin F or nucleic acid
in spirulina act as oxygen-carrier to several cells through body and directly
effect the hair, skin and nails.
Anti-virus
Several researches from Medical and Pharmaceutical University in Toyama, Japan
found that calcium extracted from spirulina gives best result in treating
several kinds of virus, such as uticaria influenza, mump, german measles,
etc.
Sexual improvement and reproduction
Eating insufficient food might affect sex hormones production. Spirulina consists
of Zinc and amino acids that help to promote sexual capacity.
Tryptophan (amino acid)
Increase sexual energy and enhance sexual confidence
for male
Arginine (amino acid)
Existing 80 % in male sperm, lacking of this amino
acid may cause impotence or sterility
Anti-allergy
Pantothenic acid in spirulina can excellently help in preventing allergy or
infection, allowing the patient to have better life.
Renal nourishment
Spirulina consists of phosphorus 8,000 mg/g as our body needs 1 g of phosphorus
to jointly use with other vitamins to destroy limestone in the body caused
by uric acid accumulation, and then clean up the renal tube to reduce gout
and gallstone in kidney. In addition, phosphorus is a factor helping the
phosphorelation process for better function of kidney.
Suitable for the golden age-old age person
The continuous lack of nutrients from proteins, vitamins and mineral salts
including the decreasing in absorption capacity and menopause condition may
affect to the change of hormones. Spirulina is only one food in the world
that mostly like the drug prolongs life; replenish body to become distinctively
young.
Cancer resistance
Cancer is considered as the second serious disease that killed human being
before appropriated age. Spirulina consists of beta-carotene preventing cancer
as well as phycocyanin and chlorophyll resisting the growth of cancer cells.
Abate inflamed stomach
Spirulina composes of high chlorophyll, which helps to heal the wound in bladder
and reduce the swollen tissue. Mesafirine, the substance found in spirulina
also help to treat the wound in bladder.
Liver nourishment
Liver needs high proteins for functioning. As spirulina consisted of methionine,
essential amino acid, to restore the liver cells being recovered from hepatitis
or other liver diseases, which almost found to be the dangerous disease.
|
|
 |
|
- Consisted of protein which is 4 times higher
than protein in meat and 5 times more than egg.
- Consisted of 8 amino acids which can not
be completely produced by our body,
so-called essential
amino acid
- Consisted of beta-carotene which is a source
of vitamin A, that is 20-25 times more
than in carrot.
- Consisted of vitamins and mineral salts
at appropriate quantity upon comparing
with other food.
- Consisted of vitamin B1 more than 100
times comparing with vegetables,
fruit and some
animals
- Consisted of vitamin B2 which is
5-20 times more than other foods
- Consisted of vitamin B12 that helps
to enhance good memory
and also prevent serious
anemia. Most people
take vitamin B12 from
animal livers, but spirulina consists of vitamin
B12 which
is 2.5 times more than
in those animal livers.
Additionally, it is suit for brain and
also appropriate for the vegetarians as well.
- Consisted of gamma-linolenic
acid (GLA) which is an
important fatty
acid to reduce
cholesterol, prevent
hypertension, cardiopathy
and free from toxic substances.
Spirulina helps to nourish brain
for good health.
Amino acid is the organic substance daily desired
by our body. Spirulina consisted of 8 essential amino
acids that cannot be produced by our body. Lacking
of these amino acids consequently will result in the
lack of raw materials that produce hormones and support
brain. Insufficient amino acids will cause several
diseases. As spirulina is composed of complete amino
acids, it can replenish the nervous system, protect
the brain cell and improve the brain system.
|
|
 |
|
| Protein 60-70 % by dry weight |
Consisted of completed amino acids
essentially for body and can be 4 times easily
digested compared to protein from meat ad bean |
| Essential amino acids |
Amino acids, which cannot be synthesized
by, body |
| Isoleucine 4.13 % |
Promote growth of body, develop
brain cells, keep balance of nitrogen, synthesize
other essential amino acids, prevent the deterioration
of nervous system and develop IQ |
| Leucine 5.50 % |
Activate functions of upper brain
and stimulate body functions |
| Lysine 4.0 % |
Create antibody and immunity replenish
liver texture, improve cell growth and repair damage
cells |
| Methionine 2.17 % |
Help to digest fat improve health
and reduce stress |
| Phenylalanine 3.95 % |
Improve functions of thyroid gland
to activate body mechanism, being hormone consisted
of iodine to activate body to be healthier, better
emotion and memory, improve hair growth to be stronger,
and also moisturize dry skin along with reduce
inflammation from sunburn |
| Threonine 4.17 % |
Contribute function of digestive
system, especially intestine for more efficient
absorption |
| Tryptophan 1.13 % |
Support body to take vitamin B,
good sleep and reduce stress |
| Valines 6.0 % |
Activate the brain capacity, combine
the muscle interaction, reduce muscle pain or inflamed
wound and also promote emotional relaxing |
| Non-essential amino acids |
Amino acids, which can be synthesized
by our body, such as enzyme, protein, hormone and
chemical substances in brain |
| Alanine 5.82 % |
Help to strengthen cell membrane,
activate bone marrow, originate red blood cells,
reduce risk of anemia, build up immune response
and burn down sugar and organic acids in body |
| Arginine 5.98 % |
Important to male sexual ability
because sperm consists of 80 % arginine; moreover,
help to detoxify blood in body |
| Cystine 0.67 % |
Help to improve pancreas, reduce
allergic and problem from starvation |
| Glutamic acid 8.94 % |
One of major energy of brain cells
like glucose, control alcohol level in body and
brain health |
| Glycine 3.46 % |
Help to raise energy and oxygen
in body cells |
| Histidine 1.08 % |
Improve functions of nervous system,
especially the organs related to the listening
ability |
| Proline 2.97 % |
Being the precursor of glutamic
acid |
| Serine 4.0% |
Serve the capacity of brain cell
membrane and protect nerve fibers |
| Tyrosine 4.60% |
Slow down cell growth and regulate
the hunger feeling in Hypothalamus gland of lower
brain |
|
|
|
 |
|
| Summary report of researches
and testing results related to spirulina
According to “ The Secrets of Spirulina Medical
Discoveries of Japan Doctor” by Christopher Hills,
Ph.D., D.Sc. (Translated paper Volume No. 105 of the
National Research Commission Office, in the field of
Agriculture and Biology)
|
Research group
|
Research topic
|
Research / testing method
|
Result of research / testing
|
| 1. Dr. Takaya Takuishi, M.D., Ph.D., National Medical
and Dental Science University, Tokyo, 1977 |
Spirulina and the reduction of sugar level in blood |
Spirulina was given to the serious diabetes patients
by taking 7 tablets after meal, 3 times a day simultaneously
with strictly control of food consumption for 60
days. |
The sugar level in almost patients was significantly
reduced to normal level. |
| 2. Minoru Tanaka, Kyoto Medical Science University |
Spirulina and treatment of pancreatitis |
Spirulina was taken by 2 inflamed pancreatic patients
which the former was vomited, had stomachache on
the upper part and continuously diarrhea for a year.
The latter patient was seriously felt stomachache
on the upper part, sometimes diarrhea and had backache
at least 2 times a week. The treatment had done by
giving the patients to take spirulina 21 tablets
a day. |
These two patients were gradually recovered. Diarrhea
in the first patients was reduced within 2 weeks
and no vomiting at the end of 5th week. The stomachache
in the second patients was recovered within 3 weeks
but still be pain sometimes and then after 6 weeks,
stomachache was totally recovered |
3. Yoshida Yamasaki,
M.D., Medical and Dental Science University, Tokyo,
Director of Kazuo Optic Hospital, Yamasaki, 1966
|
Spirulina and optic problems |
Spirulina was supplied with ophthalmic medicine
to the optic patients, for example, cataract, bleeding
at retina, etc by taking 10 tablets after meal, morning
and evening time. In case of serious symptom, take
10 tablets after 3 meals. |
90 % from 480 patients were recovered and had better
sight. Blood pressure and clogged blood vessel were
reduced to normal.
|
| 4. Dr. Seshadri of Marugap, Cheltar Center, Madras,
India |
Spirulina and optic problems |
Spirulina was taken by pre-school children who
suffering from night blindness caused by lacking
of vitamin A (total 5,000 people within 1 year) |
The optic problem was reduced from 10-80 % of total
children. |
| 5. Dr. Iwao Tanabe, Psychologist and intern doctor,
Denensofu Nursing Home |
Spirulina and treatment of hair loss |
Spirulina was brought to the patients 6 tablets
a day. |
The symptom was gradually recovered within 9 weeks,
and the newborn hair became blacken in the 10th week. |
| 6. Prof. Tomogishi Sakai, Ph.D., Intern doctor
and anatomist of Eastern Japan University |
Spirulina and treatment of esophageal and gastropathy |
Spirulina was consumed by 5 patients of gastropathy
with 5 tablets per meal, preferable simultaneously
eat with food for 3 meals. |
Most of the patients were recovered from stomachache. |
| 7. Nobusu Ijima, Professor in Saint Marry Anne
Medical Science University |
Spirulina and disposal of alcohol in the body |
Spirulina was given to the subjected groups approximately
4-5 tablets before drinking. |
No hangover remained after drinking. |
| 8. Japan |
Spirulina and anemia |
Spirulina was taken by 8 female patients who had
less red blood cells, 8 tablets after 3 meals for
30 days |
Red blood cell production in all patients was increased
from 10.9 to 13.2, which is considered as the normal
level. |
| 9. Dr. Christopher Hill, Ph.D., University of the
Trees |
Safety of spirulina |
Dr. Hill and his 50 students had starved and eaten
only spirulina for 30-107 days |
All of them did not have any problem or side effects
after consuming. |
| 10. Toru Matsui, Japanese Philosopher |
Safety of spirulina |
Toru Matsui had not eaten any food, except spirulina
and other types of algae for over 15 years. |
Toru Matsui still alive without any side effect. |
| |
|
|
 |
|
The Spirulina
Health Library contains over 200 published scientific
references covering
35 years of international researches. It is solely
for education. It is not intended s medical
advice or as a guide for self-treatment. Consult
a qualified healthcare practitioner for
diagnosis or treatment of any disease or medical
condition.
Anti-viral Studies
-
Inhibition of HIV-1 replication by an
aqueous extract of spirulina (Arthrospira
paltensis)
Ayehunie S.1, Belay A.2, Hu Y.1, Baba T.1,3, Ruprecht R.1
1Laboratory of Viral Pathogenesis, Dana-Farber Cancer Institute and Harvard
Medical School, Boston, MA, USA.
2Earthrise Farms, Calipatria, CA, USA.
3Division of Newborn Medicine, Department of Pediatrics, Tufts University,
Boston, MA, USA.
Water extract of spirulina strain Platensis (Arthrospira
platensis)
inhibits HIV-1 replication in human derived T-cells and in human
peripheral blood
mononuclear cells. A concentration of 5-10 mcg/mi was found to reduce
viral production
and/or syncytium formulation of about 50 %, and a concentration of
100 mcg/ml show a 90-100 % inhibition without cytotoxicity. The 50
% inhibitory
concentration
(IC50) for cell growth was computed to be between 2-6.5 mg/ml depending
on the cell types used; the therapeutic index was >100. The extract
also blocked Rauscher murine leukemia virus (RL V)-induced plaque
by 95 % at concentrations
ranging from 75-150 mcg/ml. The 50 % reduction in plaque formation
(50 % effective concentration or EC50) was at a concentration of
9-30 mcg/ml.
The extract directly
inactivated HIV-1 infectivity when preincubated with virus prior
to addition with human T-cell lines at similar inhibitory concentrations.
- An extract from spirulina is a selective
inhibitor of Herpes Simplex virus type
1 penetration into Hela cells
Hayashi et al. 1993. Pub. in Phytotherapy
Research, Vol. 7, p. 76-80, Japan
The water-soluble extract of spirulina
achieved a dose-dependent inhibition
of the replication of Herpes Simplex
virus type 1 (HSV-1) in Hela cells within
the concentration ranges of 0.08-50 mg/ml. This extract proved to
have no virucidal
activity and did not interfere with adsorption to host cells. However,
the extract affected to viral penetration
in a dose-dependent manner. At 1 mg/ml
the extract was found to inhibit virus-specific protein synthesis
without suppressing
host cell protein synthesis if added to the cells 3 hours before
hamsters at doses of 100 and 500 mg/kg
a day.
- AIDS antiviral sulfolipids from cyanobacteria
(blue green algae)
K. Gustafson et
al. August 16, 1989.
Pub. in journal of the National Cancer
Institute, Vol. 81(16) p. 1254, USA.
Sulfoglycolipids from blue green algae exhibit strong antiviral
properties. Helper T-cells exposed to blue green algae sulfoglycolipids
were protected
from HIV-1 infection in vitro studies.
Beta-carotene, Cancer Prevention and Health Improvement
- Bioavailability of spirulina carotenes
in pre-school children
V. Annapurna et al. 1991. National Institute of
Nutrition, Vol. 10, p. 145-151, India.
The bioavailability of total carotenes
and beta-carotene from spirulina was examined
in apparently healthy preschool children
and found to be comparable
to those value reported for other plant sources like leafy vegetables
and carrots. The study also showed spirulina
is a good source of vitamin A, as there
was
a significant increase in serum retinal levels. Researchers concluded
that spirulina can be used as a source
of vitamin A for dietary supplement, is
relatively
inexpensive, has higher beta-carotene than any other plant sources
and can be cultivated throughout the year.
- Inhibition of experimental oral carcinogenesis
by topical beta-carotene
Schwartz et al. 1986. Harvard School
of Dental Medicine, Pub. In Carcinogenesis,
May 1986, Vol. 7 (5), p. 711-715, USA.
Beta-carotene was found to significantly inhibit the formation of
squamous cell carcinoma of hamster buccal pouch when a solution was
applied topically
three times weekly for 22 weeks in an experiment with 4 hamsters.
In a second experiment with 80 hamsters, beta-carotene was found
to inhibit oral carcinogenesis
in an initiation-promotion hamsters buccal pouch system. Beta-carotene
inhibited both initiation and promotion of carcinogenesis.
Cholesterol Reduction
-
Cholesterol lowering effect of spirulina
N. Nayaka et al. 1988. Tokai University. Pub. In Nutrition Reports Int’l,
Vol. 37, No. 6, p. 1329-1337, Japan.
Thirty healthy men with high cholesterol, mild hypertension and hyperlipidemia
showed lower serum cholesterol, triglyceride and LDL (undesirable fat)
levels after eating spirulina for eight weeks. These men did not change
their diet,
except adding spirulina. No adverse effects were noted. Group A consumed
4.2 grams daily for eight weeks. Total serum cholesterol dropped a
significant 4.5 % within 4 weeks from 244 to 233. Group B consumed
spirulina for four
weeks,
then stopped. Serum cholesterol levels decreased, then returned to
initial level. Researchers concluded spirulina did lower serum cholesterol
and
was likely to have a favorable effect on alleviating heart disease
since the arterioscelosis
index improved.
- Clinical and biochemical evaluations
of spirulina with regard to its application in
the treatment of obesity
E. W. Becker et
al. 1986. Inst. Chem. Pfanz.
Pub. In Nutrition Reports Int’l,
Vol. 33, No. 4, p. 565, Germany.
- The effect of spirulina on reduction of
serum cholesterol
N. Nayaka et
al. 1986. Tokai University. Pub. In Progress in Medicine, Vol.
36, No. 11, Japan.
- Current knowledge on potential health
benefits of spirulina
Amha Belay and Yoshimical Ota 1993. Pub. in Journal of Applied Phycology, Vol.
5, p. 235-241, USA.
Spirulina is a microscopic algae, produced commercially and sold as a food
supplement around the world. Until recently, interest in spirulina was mainly
in its nutritive value. This is a critical review of data on therapeutic effects
of spirulina, ranging from reduction of cholesterol and cancer to enhancing
the immune system, increasing intestinal lactobacilli, reducing nephrotoxicity
by heavy metals and drugs as well as radiation protection.
- Spirulina: a model for micro algae as
human food
Alan Jassby 1988. In Algae and Human Affairs. Edited by Lembi and Waaland.
Pub. By Cambridge University Press, Cambridge, UK.
This is an evaluation of the food potential of micro algae using proven
technology. Numerous examples of traditional use of inland micro algae
are cited from
more than 15 countries. The nutritional aspects of spirulina stand out.
Spirulina’s
safety for human consumption, food applications, economics and environmental
aspects, world spirulina production, production costs and therapeutic
applications are reviewed. How micro algae can address world hunger problems
is addresses
with mention of harvesting wild algae and village scale production systems.
- Enhancement of antibody production
in mice by dietary spirulina
Hayashi et
al. June 1994. Kagawa Nutrition University, Japan. Pub. In Journal
of Nutrition Science and Vitaminology, Japan.
Mice fed a spirulina diet showed increased numbers of spleenic antibody-producing
cells in the primary immune response to sheep red blood cells (SRBC). However,
immunoglobulin G (IgE)-antibody production in the secondary immune response
was hardly affected. The percentage of phagocytotic cells in peritoneal macrophages
from the mice fed spirulina diet, as well as the proliferation of spleen cells,
was significantly increased. Addition of hot-water extract of spirulina (SHW)
to an in
vitro culture of spleen cells markedly increased proliferation these
cells, whereas culture of thymus cells was scarcely affected. The spirulina
extract also significantly enhanced interleukin-1 (IL-1) production from peritoneal
macrophages. Addition to the in vitro spleen cell culture of SHW as well as
the supernatant of macrophages stimulated with SHW resulted in enhancement
of antibody production that is an increase of the number of PFC. These results
suggest that spirulina enhances the immune response, particularly the primary
response, by stimulating functions, phagocytosis and IL-1 production.
- Immunostimulating activity of lipopolysaccharides
from blue green algae
L. Besednova et
al. 1979. Pub in Zhurnal Mikrobiologii, Immunobiologii, Vol.
56 (12), p. 75-79, Russia.
The whole cells of blue green algae and lipopolysaccharides (LPS) isolated
from these cells were shown to stimulate the production of microglobulin antibodies
in rabbits. The macro- and microphage indices in rabbits increased significantly
after the injection of LPS isolated from blue green algae 24-48 hrs before
injecting the animals with a virulent Y.
pseudotuberculosis strain. Besides,
the inhibiting action of this strain on the migration of phagocytes to the
site of infection was abolished immediately after the injection. The use of
the indirect hemaglutination test allow to provide the absence of close antigenic
interrelations between blue green algae and the following organisms: Spirulina
platensis, Microcystis aeruginosa, Phormidium
africanum and P. uniccinatum.
- Study on effect and mechanism of polysaccharides
of spirulina on body immune function improvement
G. Baojiang et
al. April 1994. South China Normal University. Pub. In Proceed
of Second Asia Pacific Conference on Algal Biotechnology, University of Malaysia,
p. 33-38, China.
Polysaccharides of spirulina, at the dosage of 150-300 mg/kg, by injection
or taking orally, can increase the phagocyte percentage index of abdominal
macrophage, the percentage of T-lymphocyte and haemolysin content in the peripheral
blood of mouse. These results demonstrate polysaccharides can improve both
the nonspecific function of cellular immunity and the specific hormonal immunity.
The mechanism seems related to fact that polysaccharides can enhance reproductive
ability of marrowcyte, growth of thymus and spleen, biosynthesis of serum protein,
and that polysaccharide can eliminate the inhibition effect of inhibitive circular
phosphamide on immune system of body.
- Clinical experiences of administration
of spirulina to patients with hypo chronic
anemia
T. Takeuchi et al. 1978. Tokyo Medical and Dental University, Japan.
Eight women had been limiting their meals to stay thin and were showing hypo
chronic anemia-lower than normal blood hemoglobin content. They took four grams
of spirulina after each meal. After 30 days blood hemoglobin content increased
21 % from 10.9 to 13.2, a satisfactory level, no longer considered anemic.
Kidney Detoxification
- Effect of spirulina on the renal toxicity
induced by inorganic mercury and cisplatin
H. Fukino et
al. 1990. Pub. In Eisei Kagaku, Vol.
36 (5), 1990. Japan.
Kidney toxicity caused by mercury was suppressed by feeding spirulina to rats.
A water-soluble extract of spirulina, containing phycocyanin, the natural blue
pigment, was examined. Renal (kidney) toxicity in rats caused by para-aminophenal
(pain reliever) and cisplatin (anti-cancer) was significantly reduced by the
phycocyanin extract of spirulina. Researchers concluded that phycocyanin plays
a major role in the protective effect of spirulina against renal failure caused
by mercury and pharmaceutical drugs, and that spirulina might be applicable
to the general renal disfunction.
- Effectiveness of spirulina algae as
food for children with protein-energy malnutrition
in
a tropical environment
P. Bucaille 1990. University Paul Sabatier,
Toulouse, France.
- The study on curative effect of zinc
containing spirulina for zinc deficient children
Yonghuang et
al. 1994. Capital Medical College,
Beijing. Presented at 5th Int’l
Phycological Congress, Qingdao, June 1994, China.
Spirulina with high zinc content may be twice as effective as a zinc
supplement in curing zinc deficiency in children. The effective dose
of zinc from
spirulina was 2 to 4 times less than the zinc from a common supplement,
zinc sulfate.
More than two times the children were cured with high zinc spirulina.
One hundred children were diagnosed as suffering from zinc deficiency.
For
a three-month
period, 50 children were given zinc sulfate and 50 were given spirulina
tablets. Doctors concluded spirulina’s effect was much better
than zinc sulfate. Spirulina had no side effects and was easy to administer
for long periods of
time. They theorized that high zinc spirulina had many bioactive and
nutritious
substances, which improved mineral absorption, general health and the
immune system.
Polysaccharides and Immune System Improvement
- Calcium spirulina, an inhibitor of
enveloped virus replication, from a blue green
algae
spirulina
Hayashi et al. 1996. Pub. In Journal of Natural Products, Vol. 59, p. 83-87.
Japan.
Bioactivity is directed from fractionation of a hot water extract of blue green
algae. Spirulina strain platensis led to the isolation of a novel sulfated
polysaccharide named calcium spirulina (Ca-SP) as an antiviral principle. This
polysaccharide was composed of rhamnose, ribose, mannose, fructose, galactose,
xylose, glucuronic acid, galacturonic acid, sulfate and calcium. Ca-SP was
found to inhibit the replication of several enveloped viruses, including Herpes
Simplex virus type 1, human cytomegalovirus, measles virus, mump virus, influenza
A virus and HIV-1. It was revealed that Ca-SP selectively inhibited the penetration
of virus into host cells. Retention of molecular conformation of calcium ion
with sulfate groups was suggested to be indispensable to its antiviral effect.
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